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Merck

CACNA1E

calcium channel, voltage-dependent, R type, alpha 1E subunit

同義詞:
BII, CACH6, CACNL1A6, Cav2.3
物種:
UniProtKB ID:
基因 ID:
  • Human(777) Summary: Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • Mouse(12290) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Rat(54234) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Zebrafish(567702) voltage-dependent R-type calcium channel subunit alpha-1E
  • cow(353113) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic cat(101093985) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • dog(490305) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • chicken(424412) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • naked mole-rat(101701145) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • domestic guinea pig(100716749) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • sheep(101102503) calcium channel, voltage-dependent, R type, alpha 1E subunit
  • Domestic Rabbit(100009403) calcium channel, voltage-dependent, R type, alpha 1E subunit

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Small Molecule - Allosteric Modulator

產品編號
描述
物種
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物種
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物種
human
加巴喷丁标准液 CRM 溶液, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-Dihydropyridine Receptor (α1 Subunit) antibody produced in mouse, clone 1A, buffered aqueous solution,
物種活性
guinea pig, human, mouse, rabbit, rat
應用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

產品編號
描述
物種
维拉帕米 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物種
human
苯磺酸氨氯地平, ≥98% (HPLC),
物種
human
苯磺酸氨氯地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
苯磺酸氨氯地平(钙拮抗药), United States Pharmacopeia (USP) Reference Standard,
物種
human
尼卡地平 盐酸盐, powder, ≥98%,
物種
human