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Merck

CACNA1D

calcium channel, voltage-dependent, L type, alpha 1D subunit

同義詞:
CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, SANDD
物種:
UniProtKB ID:
基因 ID:
  • Human(776) Summary: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
  • Mouse(12289) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Rat(29716) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • chicken(395895) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Horse(100051186) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • cow(408013) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic cat(101088394) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • dog(484724) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • sheep(101106371) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • Domestic Rabbit(100327259) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • domestic guinea pig(100726255) calcium channel, voltage-dependent, L type, alpha 1D subunit
  • naked mole-rat(101714832) calcium channel, voltage-dependent, L type, alpha 1D subunit

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Small Molecule - Allosteric Modulator

產品編號
描述
物種
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物種
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
加巴喷丁标准液 CRM 溶液, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
非洛地平, United States Pharmacopeia (USP) Reference Standard,
物種
human
尼莫地平, United States Pharmacopeia (USP) Reference Standard,
物種
human
非洛地平, European Pharmacopoeia (EP) Reference Standard,
物種
human
尼莫地平, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
尼莫地平, European Pharmacopoeia (EP) Reference Standard,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-CACNA1D antibody produced in mouse, clone S48A-9, 1 mg/mL, purified immunoglobulin,
物種活性
human, mouse, rat
應用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Calcium Channel (α1D Subunit) (L-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物種活性
mouse, rat
應用
immunocytochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Blocker

產品編號
描述
物種
Margatoxin, ,
物種
mouse, rat, human
维拉帕米 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物種
human
苯磺酸氨氯地平, ≥98% (HPLC),
物種
human
苯磺酸氨氯地平(钙拮抗药), United States Pharmacopeia (USP) Reference Standard,
物種
human
尼卡地平 盐酸盐, powder, ≥98%,
物種
human