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BACE1

beta-site APP-cleaving enzyme 1

同義詞:

ASP2, BACE, HSPC104

物種:

Human BACE1 (23621), Mouse Bace1 (23821), Rat Bace1 (29392), Zebrafish bace1 (403005), cow BACE1 (614333), Horse BACE1 (100071137), domestic cat BACE1 (101086840), dog BACE1 (489390), chicken BACE1 (419768), sheep BACE1 (101119667) ...更多

UniProtKB ID:

P56817, A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1

基因 ID:

Human(23621) Summary: Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
Mouse(23821) beta-site APP cleaving enzyme 1
Rat(29392) beta-site APP cleaving enzyme 1
Zebrafish(403005) beta-site APP-cleaving enzyme 1
cow(614333) beta-site APP-cleaving enzyme 1
Horse(100071137) beta-site APP-cleaving enzyme 1
domestic cat(101086840) beta-site APP-cleaving enzyme 1
dog(489390) beta-site APP-cleaving enzyme 1
chicken(419768) beta-site APP-cleaving enzyme 1
sheep(101119667) beta-site APP-cleaving enzyme 1
Domestic Rabbit(100343442) beta-site APP-cleaving enzyme 1
naked mole-rat(101701890) beta-site APP-cleaving enzyme 1
domestic guinea pig(100135485) beta-site APP cleaving enzyme 1

產品 (16)
同儕審查論文 (821)

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ELISA

產品編號

描述

物種

人BACE1 /β-分泌酶1 ELISA试剂盒, ,

物種

human

Activity Assay

產品編號

描述

物種

β-分泌酶(BACE1) 活性检测试剂盒（荧光法）, 1 kit sufficient for 250 reactions,

物種

human

Antibodies

產品編號

描述

物種活性

應用

Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,

物種活性

human

應用

western blot

抗-BACE抗体，CT，克隆61-3E7, clone 61-3E7, Chemicon^®, from mouse,

物種活性

human, mouse, primate, rat

應用

immunoprecipitation (IP)
western blot

Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,

物種活性

human

應用

microarray
western blot

抗-BACE1 兔抗, affinity isolated antibody,

物種活性

bovine, dog, guinea pig, horse, human, mouse, rabbit, rat

應用

immunofluorescence
immunohistochemistry
western blot

Anti-BACE Antibody, CT, Chemicon^®, from rabbit,

物種活性

human

應用

immunohistochemistry
western blot

Small Molecule - Inhibitor

產品編號

描述

物種

(−)-儿茶素没食子酯酸, ≥98% (HPLC), from green tea,

物種

human

(-)-儿茶素, ≥97% (HPLC), from green tea,

物種

human

(−)-表儿茶素, ≥90% (HPLC),

物種

human

(−)-表儿茶素, ≥98% (HPLC), from green tea,

物種

human

Kits

產品編號

描述

物種

β-分泌酶(BACE1) 活性检测试剂盒（荧光法）, 1 kit sufficient for 250 reactions,

物種

human

Proteins

產品編號

描述

物種

β-分泌酶人, recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000 units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution,

物種

human