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Merck

ANPEP

alanyl (membrane) aminopeptidase

同義詞:
APN, CD13, GP150, LAP1, P150, PEPN
物種:
UniProtKB ID:
基因 ID:
  • Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Mouse(16790) alanyl (membrane) aminopeptidase
  • Rat(81641) alanyl (membrane) aminopeptidase
  • chicken(395667) alanyl (membrane) aminopeptidase
  • domestic cat(493785) alanyl (membrane) aminopeptidase
  • Horse(100050397) alanyl (membrane) aminopeptidase
  • cow(404191) alanyl (membrane) aminopeptidase
  • dog(403913) alanyl (membrane) aminopeptidase
  • sheep(101104860) alanyl (membrane) aminopeptidase
  • Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
  • domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
  • naked mole-rat(101706035) alanyl (membrane) aminopeptidase

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Antibodies

產品編號
描述
物種活性
應用
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
物種活性
human
應用
flow cytometry
CD13 (SP187) Rabbit Monoclonal Antibody, ,
物種活性
human
應用
immunohistochemistry
Anti-CD13 antibody, Rabbit monoclonal, clone SP182, recombinant, expressed in proprietary host, affinity isolated antibody,
物種活性
human, pig, rabbit
應用
flow cytometry
immunohistochemistry
Monoclonal Anti-CD13 antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
物種活性
human, nonhuman primates
應用
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Monoclonal Anti-CD13-APC antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
物種活性
human, nonhuman primates
應用
flow cytometry

Small Molecule - Inhibitor

產品編號
描述
物種
放线酰胺素, ,
物種
human
N-[(2S,3R)-3-氨基-2-羟基-4-苯基丁酰基]-L-亮氨酸, 97%,
物種
human, mouse, rat
黄酮, ≥99.0%,
物種
human, rat, mouse