1093001

Carbamazepine

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 5H-Dibenz[b,f]azepine-5-carboxamide
• Empirical Formula (Hill Notation): C₁₅H₁₂N₂O
• CAS Number: 298-46-4
• Molecular Weight: 236.27
• MDL number: MFCD00005073
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749228
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: carbamazepine
• manufacturer/tradename: USP
• mp: 191-192 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: NC(=O)N1c2ccccc2C=Cc3ccccc13
• InChI: 1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
• InChI key: FFGPTBGBLSHEPO-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carbamazepine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Carbamazepine Extended-Release Tablets
• Carbamazepine Oral Suspension
• Carbamazepine Tablets
• Oxcarbazepine
• Oxcarbazepine Oral Suspension
• Oxcarbazepine Tablets

Biochem/physiol Actions

Anticonvulsant; ligand for the GABA_A receptor benzodiazepine modulatory site. Sodium channel inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H302,H317,H334,H336,H360FD
• Precautionary Statements: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1A - Resp. Sens. 1 - Skin Sens. 1A - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable