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Key Documents

SCP0022

Sigma-Aldrich

ANP [Des18-22] 4-23 Amide rat

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About This Item

Empirical Formula (Hill Notation):
C64H107N25O19S2
Molecular Weight:
1594.82
UNSPSC Code:
51111800
NACRES:
NA.32

Assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥70%

storage condition

protect from light

storage temp.

−20°C

Amino Acid Sequence

Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2

Application

Atrial natriuretic peptide (ANP) is a 28 amino acid polypeptide vasodilator involved in water, sodium, potassium homeostasis. ANP mediates its actions via three receptor types: two guanylyl cyclase receptors know as NPR1 and NPR2 and a natriuretic peptide clearance receptor (NPR3/NPRC). ANP (4-23) is a selective agonist of natriuretic peptide receptor subtype NPR-C.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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