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Key Documents

SAB3501041

Sigma-Aldrich

Anti-FGFR3 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-ACH, Anti-CD333, Anti-CEK2, Anti-HSFGFR3EX, Anti-JTK4

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 89 kDa

species reactivity

mouse, rat, human

concentration

1 mg/mL

technique(s)

ELISA: suitable
immunoblotting: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

NCBI accession no.

NP_001156685

UniProt accession no.

P22607

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FGFR3(2261)

Immunogen

Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FGFR3.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3501041.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Pricing

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Nicholas Turner et al.
Nature reviews. Cancer, 10(2), 116-129 (2010-01-23)
Fibroblast growth factors (FGFs) and their receptors control a wide range of biological functions, regulating cellular proliferation, survival, migration and differentiation. Although targeting FGF signalling as a cancer therapeutic target has lagged behind that of other receptor tyrosine kinases, there
G A Bellus et al.
Nature genetics, 10(3), 357-359 (1995-07-01)
Hypochondroplasia (MIM 146000) is an autosomal dominant skeletal dysplasia with skeletal features similar to but milder than those seen in achondroplasia. Within the past year, the achondroplasia locus has been mapped to 4p 16.3 (refs 5-7) and mutations in the
K Keegan et al.
Proceedings of the National Academy of Sciences of the United States of America, 88(4), 1095-1099 (1991-02-15)
The fibroblast growth factors are a family of polypeptide growth factors involved in a variety of activities including mitogenesis, angiogenesis, and wound healing. Fibroblast growth factor receptors (FGFRs) have previously been identified in chicken, mouse, and human and have been
A Superti-Furga et al.
European journal of pediatrics, 154(3), 215-219 (1995-03-01)
Achondroplasia, the most common form of chondrodysplasia, has been associated with mutations in the gene of the fibroblast growth factor receptor-3 (FGFR-3) on chromosome 4p. All 39 achondroplasia alleles studied so far carried point mutations which caused the same amino

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