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L9151

Sigma-Aldrich

Lys-Lys-Lys-Lys-Lys

≥55% peptide basis, Bioreagent

Synonym(s):

Lys5, Pentalysine

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About This Item

Empirical Formula (Hill Notation):
C30H62N10O6
CAS Number:
19431-21-1
Molecular Weight:
658.88
MDL number:
MFCD00083765
UNSPSC Code:
12352209
PubChem Substance ID:
24896518
NACRES:
NA.26

product name

Lys-Lys-Lys-Lys-Lys, ≥55% peptide basis

form

powder

composition

Peptide content, ~60%

concentration

≥55% (peptide)

color

white

storage temp.

−20°C

SMILES string

NCCCCC(N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(O)=O

InChI

1S/C30H62N10O6/c31-16-6-1-11-21(36)26(41)37-22(12-2-7-17-32)27(42)38-23(13-3-8-18-33)28(43)39-24(14-4-9-19-34)29(44)40-25(30(45)46)15-5-10-20-35/h21-25H,1-20,31-36H2,(H,37,41)(H,38,42)(H,39,43)(H,40,44)(H,45,46)

InChI key

IXPHOHNWDLRFJH-UHFFFAOYSA-N

Amino Acid Sequence

Lys-Lys-Lys-Lys

Biochem/physiol Actions

Short poly-L-lysines polypeptides such as trilysine (lys3), tetralysine (tetra-L-lysine, lys4) and pentalysine (penta-L-lysine, lys5) are cationic moieties that may be used in the construction of gene delivery vectors and DNA nanoparticles.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Haizhen Zhang et al.
The journal of physical chemistry. A, 113(8), 1508-1517 (2009-02-05)
Electrospray Fourier transform ion cyclotron resonance mass spectrometry, ion mobility spectrometry, and computational methods were utilized to characterize the complexes between lysine or pentalysine with three prototypical host molecules: alpha-cyclodextrin (alpha-CD), cucurbit[5]uril (CB[5]), and cucurbit[6]uril (CB[6]). Ion mobility measurements show
M Mosior et al.
Biochimica et biophysica acta, 1105(1), 185-187 (1992-03-23)
The binding of pentalysine to phospholipid vesicles depends in a sigmoidal manner on the mole fraction of acidic lipid in the vesicles. A simple analysis demonstrates that this apparent cooperativity is probably due to both the reduction of dimensionality that
Fabiana Perocchi et al.
Nucleic acids research, 35(19), e128-e128 (2007-09-28)
Recent transcription profiling studies have revealed an unanticipatedly large proportion of antisense transcription across eukaryotic and bacterial genomes. However, the extent and significance of antisense transcripts is controversial partly because experimental artifacts are suspected. Here, we present a method to
Dan Zhao et al.
Journal of neuroinflammation, 14(1), 234-234 (2017-12-05)
It has been shown that chronic stress-induced depression is associated with exaggerated inflammatory response in the brain. Alpha7 nicotinic acetylcholine receptors (α7nAChRs) regulate the cholinergic anti-inflammatory pathway, but the role of cholinergic signaling and α7nAChR in chronic stress has not
M Roux et al.
European biophysics journal : EBJ, 16(5), 267-273 (1988-01-01)
The interaction of cationic pentalysine with phospholipid membranes was studied by using phosphorus and deuterium Nuclear Magnetic Resonance (NMR) of headgroup deuterated dimyristoyl phosphatidylcholine (DMPC) and dimyristoyl phosphatidylserine (DMPS). In the absence of pentalysine, some of the deuterium and phosphorus
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