L6135
Lectin from Arachis hypogaea (peanut)
biotin conjugate, lyophilized powder
Synonym(s):
PNA, Peanut agglutinin
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
Recommended Products
conjugate
biotin conjugate
Quality Level
form
lyophilized powder
mol wt
120 kDa
composition
Protein, ≥80% Lowry
extent of labeling
~3 mol biotin per mol protein
technique(s)
blood typing: suitable
fractionation: suitable
solubility
water: 1.00-1.10 mg/mL, clear to slightly hazy, colorless
storage temp.
2-8°C
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General description
Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea, found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.
Application
Lectin from Arachis hypogaea (peanut) has been used:
- in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine
- in Immunohistochemical double staining
- Immunohistochemical double staining for the detection of germinal centers
- in enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine
Biochem/physiol Actions
Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF) and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium. It is therefore used as tumor marker.
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.
Packaging
Package size based on protein content.
Physical form
Contains sodium citrate
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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