F5379
Fucosterol
≥93%, powder, antioxidant
Synonym(s):
3β-Hydroxy-5,24(28)-stigmastadiene, 5,24(28)-Stigmastadien-3β-ol
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About This Item
Empirical Formula (Hill Notation):
C29H48O
CAS Number:
Molecular Weight:
412.69
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
Product Name
Fucosterol, ≥93%
Quality Level
Assay
≥93%
storage temp.
2-8°C
SMILES string
C\C=C(/CC[C@H](C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C)C(C)C
InChI
1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h7,10,19-20,23-27,30H,8-9,11-18H2,1-6H3/b21-7+
InChI key
OSELKOCHBMDKEJ-QPSGOUHRSA-N
General description
Fucosterol is a phytosterol abundantly present in algae, Ecklonia arborea and Silvetia compressa.
Application
Fucosterol has been used:
- as an environmental contaminant to study its effect on morphological development in growing zebrafish embryos and larvae
- to study its anxiolytic effects in mice
- as an external standard to analyze sterols in seaweed samples
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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A Kamal-Eldin et al.
Lipids, 33(11), 1073-1077 (1998-12-31)
This work shows that fucosterol, delta5-avenasterol, and similar ethylidene-side chain sterols can undergo acid-catalyzed isomerization to give a mixture of five isomers. Four isomers formed from fucosterol were analyzed, using gas chromatography-mass spectrometry, and were characterized as delta5-avenasterol, two delta5,23-stigmastadienols
Alice A Ramos et al.
Journal of toxicology and environmental health. Part A, 82(9), 537-549 (2019-07-02)
Colorectal cancer (CRC) is one of the most frequently occurring carcinomas which require effective therapies. Fucosterol is a sterol present in marine brown seaweeds with several biological activities. However, the influence of fucosterol in CRC remains to be determined. Thus
I P Shanura Fernando et al.
Environmental research, 172, 150-158 (2019-02-21)
Particulate matter (PM) air pollution has gradually become a widespread problem in East Asia. PM may cause unfamiliar inflammatory responses, oxidative stress, and pulmonary tissue damage, and a comprehensive understanding of the underlying mechanisms is required in order to develop
H Hagiwara et al.
Biochemical and biophysical research communications, 139(1), 348-352 (1986-08-29)
The modulation of angiotensin converting enzyme (ACE) levels was studied using fucosterol, one of phytosterols, in cultured bovine carotid endothelial cells. Addition of fucosterol to the culture medium resulted in the decrease of ACE activity of endothelial cells; however, fucosterol
Cassandra D Kinch et al.
Aquatic toxicology (Amsterdam, Netherlands), 175, 286-298 (2016-04-24)
Exposure to environmental contaminants has been linked to developmental and reproductive abnormalities leading to infertility, spontaneous abortion, reduced number of offspring, and metabolic disorders. In addition, there is evidence linking environmental contaminants and endocrine disruption to abnormal developmental rate, defects
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