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EHU083031

Sigma-Aldrich

MISSION® esiRNA

targeting human METTL4

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGATCCAGGAAGGTCTCAAAAGTGGTTTTCTTTATCCACTTTTTGAAAAACAGGACAAGGGTAGTAAGCCCATTACTTTACCACTTGACGCCTGCAGTTTGTCAGAATTATGTGAAATGGCAAAGCATTTGCCTTCTCTGAATGAAATGGAACATCAGACATTACAATTGGTGGAAGAGGATACATCTGTTACAGAACAGGATTTATTTTTGCGAGTTGTTGAAAACAACTCTAGCTTTACAAAAGTGATTACTTTAATGGGACAGAAATACCTGCTACCACCGAAAAGCAGTTTTCTTTTATCTGACATTTCTTGTATGCAACCACTTCTAAACTATAGGAAAACATTTGATGTAATTGTGATAGATCCACCATGGCAGAACAAATCAGTTAAAAGAAGTAATAGGTACAGTTATTTGTCACCCCTGCAAATACA

Ensembl | human accession no.

ENSG00000101574

NCBI accession no.

NM_022840

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... METTL4(64863) , METTL4(64863)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ziyang Hao et al.
Molecular cell, 78(3), 382-395 (2020-03-19)
N6-Methyldeoxyadenosine (6mA) has recently been shown to exist and play regulatory roles in eukaryotic genomic DNA (gDNA). However, the biological functions of 6mA in mammals have yet to be adequately explored, largely due to its low abundance in most mammalian
Bo-Jhih Guan et al.
Molecular cell, 68(5), 885-900 (2017-12-09)
The integrated stress response (ISR) is a homeostatic mechanism induced by endoplasmic reticulum (ER) stress. In acute/transient ER stress, decreased global protein synthesis and increased uORF mRNA translation are followed by normalization of protein synthesis. Here, we report a dramatically

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