D3658

1,9-Dideoxyforskolin from Coleus forskohlii

≥97%, solid

• Synonym(s): 7β-Acetoxy-6β-hydroxy-8,13-epoxy-labd-14-en-11-one
• Empirical Formula (Hill Notation): C₂₂H₃₄O₅
• CAS Number: 64657-18-7
• Molecular Weight: 378.50
• MDL number: MFCD00082318
• UNSPSC Code: 41106305
• PubChem Substance ID: 24893774
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥97%
• form: solid
• optical activity: [α]26/D +93.6°, c = 6.12 in chloroform(lit.)
• color: white to off-white
• solubility: methanol: 28 mg/mL(lit.); DMSO: 3 mg/mL(lit.); chloroform: 50 mg/mL; ethanol: 6.6 mg/mL(lit.); dilute aqueous acid and base: insoluble(lit.)
• storage temp.: −20°C
• SMILES string: [H][C@@]12[C@H](O)[C@H](OC(C)=O)[C@@]3(C)O[C@](C)(CC(=O)C3[C@@]1(C)CCCC2(C)C)C=C
• InChI: 1S/C22H34O5/c1-8-20(5)12-14(24)16-21(6)11-9-10-19(3,4)17(21)15(25)18(26-13(2)23)22(16,7)27-20/h8,15-18,25H,1,9-12H2,2-7H3/t15-,16?,17-,18-,20-,21+,22-/m0/s1
• InChI key: ZKZMDXUDDJYAIB-OJPJTMFRSA-N

Description

Application

Useful as a negative control for forskolin.

Biochem/physiol Actions

Biologically inactive forskolin analog. Does not stimulate adenylyl cyclase.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves