C9755

Cytidine 5′-diphosphate sodium salt hydrate

from yeast, ≥95%

• Synonym(s): CDP sodium salt hydrate
• Empirical Formula (Hill Notation): C₉H₁₅N₃O₁₁P₂
• Molecular Weight: 403.18
• MDL number: MFCD00069770
• UNSPSC Code: 41106305
• PubChem Substance ID: 24893191
• NACRES: NA.51

Properties

• biological source: yeast
• Assay: ≥95%
• form: powder
• storage temp.: −20°C
• SMILES string: [Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(=O)OP(O)(O)=O)C(O)C2O
• InChI: 1S/C9H15N3O11P2.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);;
• InChI key: MAGSIBHRUIBONY-UHFFFAOYSA-N

Description

General description

Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK). CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis.

Application

Cytidine 5′-diphosphate sodium salt hydrate has been used:

• as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections
• in ribonucleotide reductase assay
• dCDP formation assay.

Biochem/physiol Actions

Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves