C7278
Caseinoglycopeptide from bovine casein
essentially salt-free, lyophilized powder
Synonym(s):
Bovine Casein Glycopeptide
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About This Item
form
essentially salt-free, lyophilized powder
mol wt
~7000
technique(s)
affinity chromatography: suitable
color
white
UniProt accession no.
storage temp.
2-8°C
Gene Information
cow ... CSN3(281728)
Amino Acid Sequence
Met-Ala-Ile-Pro-Pro-Lys-Lys-Asn-Gln-Asp-Lys
Application
- Bioactive Peptide in Dairy Research: Investigation into the effects of bovine caseinoglycopeptide on CD4+ T cells showcased its potential to modulate immune responses, highlighting its application in nutrition and functional food development (Otani et al., 1996).
Biochem/physiol Actions
The soluble carboxyl-terminal moiety of κ-casein. This antithrombotic peptide binds to glycoprotein GPIb in the platelet membrane, thus inhibiting platelet aggregation by blocking the binding of von Willebrand factor.
Preparation Note
Prepared by a modification of the method of Alais and Jolles.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Franz-Georg Hanisch
Analytical chemistry, 83(12), 4829-4837 (2011-04-30)
The sites of mucin-type O-glycosylation are largely unpredictable, making structural analysis by mass spectrometry (MS) indispensible. On the peptide level, a site localization and characterization of O-linked glycans in situ using tandem MS with electron-transfer dissociation or matrix-assisted laser desorption
[Comparative study of the caseinoglycopeptides formed by the action of rennin on caseins from the cow, sheep and goat. II. Study of the non-peptide portion].
C ALAIS et al.
Biochimica et biophysica acta, 51, 315-322 (1961-08-05)
K Benschop et al.
Journal of clinical microbiology, 46(12), 3965-3970 (2008-10-24)
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