Skip to Content
Merck
All Photos(1)

Documents

B6775

Sigma-Aldrich

Anti-Human IgG1−Biotin antibody, Mouse monoclonal

clone 8c/6-39, purified from hybridoma cell culture

Synonym(s):

Monoclonal Anti-Human IgG1 (Fc specific), Anti Human IgG1 - Monoclonal Anti-Human IgG1-Biotin antibody produced in mouse, Anti Human Igg1

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

mouse

conjugate

biotin conjugate

antibody form

purified from hybridoma cell culture

antibody product type

secondary antibodies

clone

8c/6-39, monoclonal

form

buffered aqueous solution

technique(s)

direct ELISA: 1:1,000

isotype

IgG2a

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Looking for similar products? Visit Product Comparison Guide

General description

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders
Monoclonal Anti-Human IgG1-Biotin antibody is specific for an epitope in the Fc region of the human IgG1. The product does not react with human IgG2, IgG3, or IgG4. This antibody clone (HP6019 clone) has been recognized as a useful human IgG1 specificity standard in the WHO/IUIS study .
The antibody is specific for the Fc portion of human IgG1 and is non-reactive with other IgG subclasses. This clone, also described as HP-6091, was found to exhibit a valuable profile of reactivity and specificity for human IgG1 by the IUIS/WHO study.

Immunogen

Fc fragment of myeloma Human IgG

Application

Monoclonal Anti-Human IgG1-Biotin antibody is suitable for use in immunoblot. The product can also be used for direct ELISA (1:1,000).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Therapeutic Administration of a Synthetic CpG
Oligodeoxynucleotide Triggers Formation of Anti-CpG
Antibodies
Karbach J, et al.
Cancer Research (2012)
Influence of camel milk on the hepatitis C virus burden of infected patients
Mohamad El-Fakharany E, et al.
Experimental and Therapeutic Medicine, 13(4), 1313-1320 (2017)
K Akuta et al.
Journal of thrombosis and haemostasis : JTH, 17(1), 206-219 (2018-11-06)
Essentials Acquired Glanzmann thrombasthenia (aGT) is generally caused by function-blocking antibodies (Abs). We demonstrated a unique aGT case due to marked reduction of αIIbβ3 with anti-αIIbβ3 Abs. The anti-αIIbβ3 Abs of the patient did not inhibit platelet function but reduced
Man-Chun Yu et al.
Pediatrics and neonatology, 54(1), 49-55 (2013-03-01)
Allergic colitis (AC) is an inflammatory condition characterized by eosinophils infiltrating the colonic wall. It can be a benign and/or severe illness among gastrointestinal diseases in infants. We report five infants who, since January 2009, in whom AC under fibrotic
D Thiagarajan et al.
ACR open rheumatology, 2(6), 344-356 (2020-05-12)
Immunoglobulin M antibodies against phosphorylcholine (anti-PCs) may be protective in atherosclerosis, cardiovascular disease (CVD), and systemic lupus erythematosus (SLE). We study immunoglobulin G1 (IgG1) and immunoglobulin G2 (IgG2) anti-PCs, with a focus on atherosclerosis and SLE. We determined anti-PCs by
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service