A6683

L-Aspartic acid sodium salt monohydrate

≥98% (TLC)

• Synonym(s): (S)-2-Aminobutanedioic acid sodium salt, Sodium L-aspartate
• Linear Formula: HO₂CCH₂CH(NH₂)CO₂Na · H₂O
• CAS Number: 323194-76-9
• Molecular Weight: 173.10
• Beilstein: 6101944
• EC Number: 223-264-0
• MDL number: MFCD00152960
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24891129
• NACRES: NA.32

Properties

• Quality Level: 200
• Assay: ≥98% (TLC)
• form: powder
• color: white
• SMILES string: [Na+].[H]O[H].N[C@@H](CC(O)=O)C([O-])=O
• InChI: 1S/C4H7NO4.Na.H2O/c5-2(4(8)9)1-3(6)7;;/h2H,1,5H2,(H,6,7)(H,8,9);;1H2/q;+1;/p-1/t2-;;/m0../s1
• InChI key: PPTHNBYUFXSJPS-JIZZDEOASA-M
• Gene Information: human ... GRIN2A(2903) ; rat ... GRIN2A(14811)

Description

General description

Aspartic acid is a non-essential amino acid. L-Aspartic acid is a dicarboxylic amino acid, which is involved in the synthesis of nerve cells proteins. It also stimulates the depolarization of nerve cell membranes. L-Aspartic acid acts as an amine donor for transamination reaction.

Application

L-Aspartic acid sodium salt monohydrate has been as a component of reservoir solution for crystallization.

Biochem/physiol Actions

Selective outflow of L-aspartic acid across the blood-brain barrier controls the level of L and D aspartic acid in the brain. Increased levels of L-aspartic acid in the brain results in excitatory neurotoxicity. Recent studies highlight that racemization of L-aspartic acid is followed by the determination of D:L ratio to estimate the age of an individual.

Principal neurotransmitter for fast synaptic excitation.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves