Skip to Content
Merck
All Photos(1)

Key Documents

87918

Sigma-Aldrich

Tetramethylrhodamine isothiocyanate mixed isomers

suitable for fluorescence, mixture of isomers

Synonym(s):

MRITC, TRITC, Tetramethylrhodamine B isothiocyanate

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C25H21N3O3S
CAS Number:
Molecular Weight:
443.52
UNSPSC Code:
12352116
NACRES:
NA.32

Quality Level

form

powder

solubility

DMSO: soluble
methanol: soluble

fluorescence

λex 529 nm; λem 596 nm in DMSO

suitability

suitable for fluorescence

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

General description

Tetramethylrhodamine isothiocyanate, also known as TRITC is a fluorescent antibody labelling agent. It is a red-fluorescing marker and can be tracked through fluorescence microscopy.

TRITC dissolves completely in DMSO at a rapid rate. And gamma globulin is unaffected to up to 30% DMSO dilution in carbonate buffer. Tetramethylrhodamine isothiocyanate doesn’t dissolve in other denaturing agents completely.

Application

Tetramethylrhodamine isothiocyanate or TRITC is used for tracking the pathway of calcium phosphate/DNA nanoparticles during cell transfection. It is an extremely intensive fluorochrome used for labeling antibodies.

Other Notes

An extremely intensive fluorochrome for labeling antibodies

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Viktoriya Sokolova et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 12(2), 174-179 (2006-10-13)
Calcium phosphate nanoparticles were prepared by precipitation from water and were then functionalized by DNA. These particles are taken up by living cells and function as gene transfer agents, i.e., the DNA is brought into a cell's nucleus and is
Haaijman, J.J.
IBRO Hand. Ser., 3, 47-47 (1983)
The conjugation of immunoglobulins with tetramethylrhodamine isothiocyanate. A comparison between the amorphous and the crystalline fluorochrome.
L Amante et al.
Journal of immunological methods, 1(3), 289-301 (1972-05-01)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service