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T6750

Sigma-Aldrich

Thioglycolic acid solution

~70 % (w/w) in H2O

Synonym(s):

Mercaptoacetic acid

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About This Item

Linear Formula:
HSCH2COOH
CAS Number:
68-11-1
Molecular Weight:
92.12
Beilstein:
506166
EC Number:
200-677-4
MDL number:
MFCD00004876
UNSPSC Code:
12352201
PubChem Substance ID:
24900401
NACRES:
NA.21

Quality Level

200

concentration

~70 % (w/w) in H2O

density

1.25 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OC(=O)CS

InChI

1S/C2H4O2S/c3-2(4)1-5/h5H,1H2,(H,3,4)

InChI key

CWERGRDVMFNCDR-UHFFFAOYSA-N

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Caution

At room temperature, concentrations over about 70% in water tend to form 1-2% thioglycolides per month which hydrolyze to the original free compound when made acid or alkaline. The 70% solution oxidizes in air but is stable at room temperature when tightly closed. Thioglycolate salts may also lose purity on storage. The exclusion of air does not materially improve stability.

Pictograms

CorrosionSkull and crossbones
GHS05,GHS06

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1B

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

266.0 °F - closed cup

Flash Point(C)

130 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBL1527
STBK9116
STBK6548
STBK4449
STBK1801

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Baofu Han et al.
Colloids and surfaces. B, Biointerfaces, 100, 209-214 (2012-07-07)
Fluorescent carbon dots (CDs) were solvothermaly synthesized in water-glycol medium by using glucose as carbon source and then modified with polyethyleneimine (PEI) for the first time to improve fluorescence quality. The as-prepared CDs were monodispersed sphere particles with a diameter
Markus Aswendt et al.
Nanomedicine (London, England), 10(16), 2499-2512 (2015-08-22)
We validated novel bimodal iron oxide particles as substitute of ferumoxides for efficient labeling of human neural stem cells (NSCs). The dextrane-coated FeraTrack Direct (FTD)-Vio particles have additional far-red fluorophores for microscopic cell analysis. MR relaxometry, spectrophotometric iron determination and
Zhengqing Liu et al.
Analytica chimica acta, 745, 78-84 (2012-09-04)
A novel fluorescent probe for Cu(2+) determination based on the fluorescence quenching of glyphosate (Glyp)-functionalized quantum dots (QDs) was firstly reported. Glyp had been used to modify the surface of QDs to form Glyp-functionalized QDs following the capping of thioglycolic
Jun-Ichi Wachino et al.
Antimicrobial agents and chemotherapy, 57(1), 101-109 (2012-10-17)
A novel subclass B3 metallo-β-lactamase (MBL), SMB-1, recently identified from a Serratia marcescens clinical isolate, showed a higher hydrolytic activity against a wide range of β-lactams than did the other subclass B3 MBLs, i.e., BJP-1 and FEZ-1, from environmental bacteria.
Heike E Friedl et al.
Biomaterials, 34(32), 7811-7818 (2013-07-28)
It was the purpose of this study to design and evaluate a chitosan derivative as mucoadhesive excipient for vaginal drug delivery systems. The chemical modification of chitosan was achieved by conjugation of thioglycolic acid (TGA) resulting in 1594 μmol thiol
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