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Key Documents

1.06281

SAFC

Sodium acetate

anhydrous, EMPROVE® ESSENTIAL, USP, FCC, E 262

Pharma Manufacturing

Synonym(s):

Sodium acetate, Acetic acid sodium salt

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About This Item

Linear Formula:
CH3COONa
CAS Number:
Molecular Weight:
82.03
Beilstein:
3595639
MDL number:
UNSPSC Code:
12352107
E Number:
E262
EC Index Number:
204-823-8

Agency

USP

Quality Level

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

autoignition temp.

1112 °F
607 °C

pH

7.5-9.2 (20 °C, 30 g/L in H2O)

pKa 

4.76 (acetic acid)

bp

>400 °C (decomposition)

mp

>300 °C (dec.) (lit.)
324 °C (decomposition)

transition temp

flash point >250 °C

density

1.52 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
solid formulation

storage temp.

15-25°C

SMILES string

[Na+].CC([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

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General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium acetate anhydrous is an acetate buffer system component commonly used in biomolecule downstream chromatography steps as well as in liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

replaced by

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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