Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

860610P

Avanti

N-18:0 Phytosphingosine

Avanti Research™ - A Croda Brand 860610P, powder

Synonym(s):

N-stearoyl 4-hydroxysphinganine (Saccharomyces Cerevisiae)

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C36H73NO4
CAS Number:
475995-75-6
Molecular Weight:
583.97
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860610P-10mg)
pkg of 1 × 5 mg (860610P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860610P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@]([H])(CCCCCCCCCCCCCC)[C@](O)([H])[C@@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)CO

InChI

1S/C36H73NO4/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-35(40)37-33(32-38)36(41)34(39)30-28-26-24-22-20-16-14-12-10-8-6-4-2/h33-34,36,38-39,41H,3-32H2,1-2H3,(H,37,40)/t33-,34+,36-/m0/s1

InChI key

IEZRNEGTKRQRFV-LFBNJJMOSA-N

General description

D-ribo-phytosphingosines or phytosphingosines (PHS) are biologically important long-chain bases present in various sphingolipids from yeasts, fungi, plants and mammals.

Application

N-18:0 Phytosphingosine has been used as a standard for the analysis of lipids from epidermis and stratum corneum in mice by mass spectrometry.

Biochem/physiol Actions

Phytosphingosine (PHS) exhibits bactericidal and anti-inflammatory activities. It prevents loss of moisture from the skin. In addition, PHS controls epidermal cell growth, differentiation and apoptosis.

Packaging

5 mL Amber Glass Screw Cap Vial (860610P-10mg)
5 mL Amber Glass Screw Cap Vial (860610P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Maria Bloksgaard et al.
Journal of lipid research, 53(10), 2162-2174 (2012-07-26)
The acyl-CoA binding protein (ACBP) is a 10 kDa intracellular protein expressed in all eukaryotic species. Mice with targeted disruption of Acbp (ACBP(-/-) mice) are viable and fertile but present a visible skin and fur phenotype characterized by greasy fur
Byung-Hak Kim et al.
The Journal of investigative dermatology, 134(4), 1023-1032 (2013-11-02)
Phytosphingosine is abundant in plants and fungi and is found in mammalian epidermis, including the stratum corneum. Phytosphingosine and its derivatives N-acetyl phytosphingosine and tetraacetyl phytosphingosine are part of the natural defense system of the body. However, these molecules exhibit

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service