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850408P

Avanti

4ME 16:0 PS

1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

Synonym(s):

1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phospho-L-serine (sodium salt); PS(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))

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About This Item

Empirical Formula (Hill Notation):
C46H89NO10PNa
CAS Number:
474967-76-5
Molecular Weight:
870.16
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (850408P-10mg)
pkg of 1 × 25 mg (850408P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850408P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O)COC(CC(C)CCCC(C)CCCC(C)CCCC(C)C)=O.[Na+]

General description

4ME 16:0 PS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine) is a sodium salt of a fatty acid modified lipid.

Application

4ME 16:0 PS (1,2-diphytanoyl-sn-glycero-3-phospho-L-serine (sodium salt)) may be used as a component in planar lipid bilayer and in asymmetrical leaflets to study the translocation of β-galactosidase (β-gal) across an asymmetric bilayer. It may be used as an internal standard in electrospray ionization-mass spectrometry (ESI-MS/MS) analysis.

Biochem/physiol Actions

Diphytanoyl lipids are mainly used in electrophysiological experiments.

Packaging

5 mL Clear Glass Sealed Ampule (850408P-10mg)
5 mL Clear Glass Sealed Ampule (850408P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Description
Pricing

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Alessio Sacconi et al.
Langmuir : the ACS journal of surfaces and colloids, 34(40), 12183-12190 (2018-09-16)
Solid supported membranes (SSMs) are usually formed by an hybrid octadecanethiol/phosphatidylcholine (PC) bilayer supported by a gold electrode. Recently, it was shown that phosphatidylserine (PS) in place of PC can promote a more effective accumulation of lipid vesicles on the
Daniel L Burden et al.
Langmuir : the ACS journal of surfaces and colloids, 34(37), 10847-10855 (2018-08-29)
All cells in all domains of life possess a cytoskeleton that provides mechanical resistance to deformation and general stability to the plasma membrane. Here, we utilize a two-dimensional scaffolding created by actin filaments to convey mechanical support upon relatively fragile
Jianjun Pan et al.
The journal of physical chemistry. B, 116(51), 14829-14838 (2012-12-04)
Cholesterol and ether lipids are ubiquitous in mammalian cell membranes, and their interactions are crucial in ether lipid mediated cholesterol trafficking. We report on cholesterol's molecular interactions with ether lipids as determined using a combination of small-angle neutron and X-ray
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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