791638C

15:0-18:1-d7-PE

Avanti Polar Lipids

• Synonym(s): 1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine
• Empirical Formula (Hill Notation): C₃₈H₆₇D₇NO₈P
• CAS Number: 2097561-15-2
• Molecular Weight: 711.01
• UNSPSC Code: 41141825
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (791638C-1mg)
• manufacturer/tradename: Avanti Polar Lipids
• concentration: 1 mg/mL (791638C-1mg)
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) is a deuterated phospholipid. The lipid comprises phosphatidylethanolamine attached to pentadecanoic acid and oleic acid. Oleic acid harbors the deuterium ions. Phosphatidylethanolamine is a membrane phospholipid and serves as an intermediate in other glycerophospholipid synthesis.

This deuterium labeled lipid is also available in a formulation of multiple lipid standards. The SPLASH^® LIPIDOMIX^® Standard includes all of the major lipid classes at ratios relative to human plasma, allowing one easy internal standard solution to be added to every sample.

Application

15:0-18:1-d7-PE (1-pentadecanoyl-2-oleoyl(d7)-sn-glycero-3-phosphoethanolamine) has been used:

• as a component of extraction solvent for lipid isolation from biological samples,
• as an internal standard for spiking serum samples for liquid chromatography with tandem mass spectrometry (LC-MS/MS)
• as an internal standard to spike plasma samples for fourier transform mass spectrometry (FTMS) analysis

Biochem/physiol Actions

Phosphatidylethanolamine (PE) regulates protein folding, protein modification, autophagy and cell division. PE serves as a substrate for glycosylphosphatidylinositol anchored proteins (GPI-APs) synthesis. Low levels of PE may be observed in Parkinson′s disease and may also inhibit protein maturation.

Packaging

2 mL Amber Glass Sealed Ampule (791638C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

LIPIDOMIX is a trademark of Avanti Polar Lipids, LLC

SPLASH is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412
• Precautionary Statements: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• Target Organs: Central nervous system
• Storage Class Code: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): does not flash
• Flash Point(C): does not flash