B48207

Bis(2-methoxyethyl)amine

98%

• Synonym(s): 2,2′-Dimethoxydiethylamine, 2-Methoxy-N-(2-methoxyethyl)ethanamine, Di(2-methoxyethyl)amine, N,N-Bis(2-methoxyethyl)amine
• Linear Formula: (CH₃OCH₂CH₂)₂NH
• CAS Number: 111-95-5
• Molecular Weight: 133.19
• Beilstein: 1736313
• EC Number: 203-923-9
• MDL number: MFCD00025906
• UNSPSC Code: 12352100
• PubChem Substance ID: 24891705
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.419 (lit.)
• bp: 170-172 °C (lit.)
• density: 0.902 g/mL at 25 °C (lit.)
• SMILES string: COCCNCCOC
• InChI: 1S/C6H15NO2/c1-8-5-3-7-4-6-9-2/h7H,3-6H2,1-2H3
• InChI key: IBZKBSXREAQDTO-UHFFFAOYSA-N

Description

Application

Bis(2-methoxyethyl)amine can be used as a reactant:

• In the Pd-catalyzed Buchwald-Hartwig amination reaction to synthesize aryl amines by reacting with aryl and heteroaryl halides.
• To synthesize α-ketoamides via metal-free oxidative coupling reaction with methyl ketones in the presence of tert-butyl hydroperoxide as an oxidant and iodine as a catalyst.
• To synthesize N, N-dialkyl perfluoroalkanesulfonamides by reacting with perfluoroalkanesulfonyl halides.
• To synthesize N-(alkoxy)succinamide ester by reacting with succinyl chloride, which can be used as an intermediate to prepare diol monomer for biodegradable polyester synthesis.

Safety Information

• Pictograms: GHS02,GHS05,GHS07
• Signal Word: Danger
• Hazard Statements: H226 - H312 - H314
• Precautionary Statements: P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 136.4 °F
• Flash Point(C): 58 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves