638617

2-(Tri-n-butylstannyl)oxazole

• Synonym(s): 2-(Tributylstannanyl)-1,3-oxazole, 2-(Tributylstannanyl)oxazole, 2-(Tributylstannyl)-1,3-oxazole, 2-(Tributylstannyl)oxazole, Tributyl(oxazol-2-yl)stannane
• Empirical Formula (Hill Notation): C₁₅H₂₉NOSn
• CAS Number: 145214-05-7
• Molecular Weight: 358.11
• MDL number: MFCD06798076
• UNSPSC Code: 12352103
• PubChem Substance ID: 24882955
• NACRES: NA.22

Properties

• refractive index: n20/D 1.4930 (lit.)
• Quality Level: 100
• bp: 108-110 °C/0.2 mmHg (lit.)
• density: 1.170 g/mL at 25 °C; 1.71 g/mL at 25 °C (lit.)
• SMILES string: CCCC[Sn](CCCC)(CCCC)c1ncco1
• InChI: 1S/3C4H9.C3H2NO.Sn/c3*1-3-4-2;1-2-5-3-4-1;/h3*1,3-4H2,2H3;1-2H;
• InChI key: YOWGRWHKDCHINP-UHFFFAOYSA-N

Description

General description

2-(Tri-n-butylstannyl)oxazole is a synthetic building block used in Stille coupling reaction.

Application

2-(Tri-n-butylstannyl)oxazole can be used as a reactant to prepare:

• Heteroaromatic compounds via Stille-Migita cross-coupling reaction with (hetero)aryl halides using a palladium catalyst.
• Ethyl 2-[3-(1,3-oxazol-2-yl)-1H-indazol-1-yl]acetate by reacting with 3-iodoindazole in the presence of Pd(PPh₃)₄ as a catalyst.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H301,H312,H315,H319,H360FD,H372,H410
• Precautionary Statements: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves