512834

3-(Hydroxymethyl)phenylboronic acid

≥95%

• Synonym(s): 3-Hydroxymethylbenzeneboronic acid
• Linear Formula: HOCH₂C₆H₄B(OH)₂
• CAS Number: 87199-15-3
• Molecular Weight: 151.96
• MDL number: MFCD01317846
• UNSPSC Code: 12352103
• PubChem Substance ID: 24873658
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95%
• mp: 95-99 °C (lit.)
• functional group: hydroxyl
• SMILES string: OCc1cccc(c1)B(O)O
• InChI: 1S/C7H9BO3/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4,9-11H,5H2
• InChI key: HGTDLKXUWVKLQX-UHFFFAOYSA-N

Description

Application

Reactant involved in:

• Copper-mediated trifluoromethylation
• Copper-catalyzed transformations from arylboronic acids in water
• Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylate

Reactant involved in the synthesis of biologically active molecules including:

• Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions
• HIV protease inhibitors with antiviral activity against drug-resistant viruses
• Pyrrole derivatives for use as PDE4B inhibitors

Other Notes

Contains varying amounts of anhydride

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves