457620

Polyglycolide

inherent viscosity 1.4dL/g

• Synonym(s): PGA, Poly(glycolic acid)
• Linear Formula: (C₂H₄O₃)_n
• CAS Number: 26124-68-5
• MDL number: MFCD00148011
• UNSPSC Code: 12162002
• PubChem Substance ID: 24869373
• NACRES: NA.23

Properties

• Quality Level: 100
• form: solid
• degradation timeframe: 6-12 months
• inherent viscosity: 1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)
• transition temp: T_m 220-230 °C
• solubility: hexafluoroisopropanol: soluble
• density: 1.53 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: OCC(O)=O
• InChI: 1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
• InChI key: AEMRFAOFKBGASW-UHFFFAOYSA-N

Description

General description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.

medical device

Physical properties

Biodegradable polymer

Preparation Note

To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves