298352

(1S)-(−)-2,10-Camphorsultam

98%

• Synonym(s): (−)-10,2-Camphorsultam, (−)-exo-10,2-Bornanesultam, (1S,5R)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.0^1,5]decane 3,3-dioxide, [3aS-(3aα,6α,7aβ)]-hexahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole-2,2-dioxide
• Empirical Formula (Hill Notation): C₁₀H₁₇NO₂S
• CAS Number: 94594-90-8
• Molecular Weight: 215.31
• Beilstein: 83811
• MDL number: MFCD00066271
• UNSPSC Code: 12352005
• PubChem Substance ID: 24857980
• NACRES: NA.22

Properties

• Quality Level: 200
• Assay: 98%
• form: solid
• optical activity: [α]19/D −32°, c = 5 in chloroform
• mp: 181-183 °C (lit.)
• SMILES string: [H][C@@]12CC[C@]3(CS(=O)(=O)N[C@@H]3C1)C2(C)C
• InChI: 1S/C10H17NO2S/c1-9(2)7-3-4-10(9)6-14(12,13)11-8(10)5-7/h7-8,11H,3-6H2,1-2H3/t7-,8-,10-/m1/s1
• InChI key: DPJYJNYYDJOJNO-NQMVMOMDSA-N

Description

General description

(1S,2R,4R)-(−)-2,10-Camphorsultam may be employed as a chiral probe for the optical resolution by HPLC and X-ray crystallographic determination of the absolute stereochemistry of carboxylic acids.

Application

(1S)-(−)-2,10-Camphorsultam may be used in the asymmetric synthesis of (S)- and (R)-N-Fmoc-S-trityl-α-methylcysteine. It may be used as proton source in the synthesis of chiral α,γ-substituted γ-butyrolactones.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves