HP
haptoglobin
Synonyms:
BP, HP2ALPHA2, HPA1S
Species:
Human HP (3240), Mouse Hp (15439), Rat Hp (24464), Zebrafish hp (566096), fruit fly hp (251278), dog HP (479668), cow HP (280692), domestic cat HP (100144610), domestic guinea pig Hp (100721435), naked mole-rat Hp (101705743) ...More
UniProtKB ID:
Gene ID:
- Human(3240) Summary: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(15439) haptoglobin
- Rat(24464) haptoglobin
- Zebrafish(566096) haptoglobin
- fruit fly(251278) humped
- dog(479668) haptoglobin
- cow(280692) haptoglobin
- domestic cat(100144610) haptoglobin
- domestic guinea pig(100721435) haptoglobin
- naked mole-rat(101705743) haptoglobin
- sheep(101102413) haptoglobin
- Domestic Rabbit(100008816) haptoglobin
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Haptoglobin antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-Haptoglobin antibody produced in mouse, clone HG-36, ascites fluid,
Species Reactivity
human
Application
ELISA
Anti-HP antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Haptoglobin antibody, Mouse monoclonal, clone HG-36, purified from hybridoma cell culture,
Species Reactivity
human
Application
ELISA
dot blot
immunoprecipitation (IP)
western blot
dot blot
immunoprecipitation (IP)
western blot
Proteins
Product Number
Description
Species
Haptoglobin Human, Phenotype 2-2, 98-100%, essentially salt-free, lyophilized powder,
Species
human
Haptoglobin Human, Phenotype 1-1, 98-100%, essentially salt-free, lyophilized powder,
Species
human