Z226173

Nucleosil^® C18 HPLC Column

5 μm particle size, L × I.D. 15 cm × 4.6 mm

• UNSPSC Code: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Properties

• Agency: suitable for USP L1
• Quality Level: 100
• product line: Nucleosil^®
• feature: endcapped
• manufacturer/tradename: Nucleosil^®
• extent of labeling: 15% Carbon loading
• parameter: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• technique(s): HPLC: suitable
• L × I.D.: 15 cm × 4.6 mm
• surface area: 350 m²/g
• matrix: octadecyl
• matrix active group: C18 (octadecyl) phase
• particle size: 5 μm
• pore size: 100 Å
• separation technique: reversed phase

Description

Application

• Quantification and Validation of Stability-Indicating RP-HPLC Method for Efavirenz: Demonstrates the utility of Nucleosil^® C18 HPLC Column in pharmaceutical analysis, particularly in quality control and stability testing of Efavirenz, ensuring compliance with regulatory standards (Gurumukhi VC, Bari SB, 2022).


• Development of new method for simultaneous analysis of piracetam and levetiracetam: This study uses the Nucleosil^® C18 column to develop robust methods for analyzing neurological medications in pharmaceuticals and biological fluids, contributing to drug stability studies (Siddiqui FA et al., 2014).


• HPLC method for determination of biologically active epoxy-transformers of treosulfan: The column′s application in plasma analysis highlights its role in pharmacokinetic studies, offering precise measurements critical for dosing and therapeutic monitoring (Główka FK et al., 2012).


• HPLC analysis of mitoxantrone in mouse plasma and tissues: Illustrates the column′s effectiveness in a pharmacokinetic study, underscoring its importance in the preclinical evaluation of cancer therapies (An G, Morris ME, 2010).


• Development and validation of an HPLC method for vancomycin: This application in a pharmacokinetic study highlights the column′s critical role in the development and validation of methods for antibiotic analysis, ensuring therapeutic efficacy and safety (Jesús Valle MJ et al., 2008).

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Legal Information

Nucleosil is a registered trademark of Macherey-Nagel GmbH & Co. KG