P8629

5β-Pregnane-3α,17α,20α-triol

• Synonym(s): 3α,17α,20α-Trihydroxy-5β-pregnane, Pregnanetriol
• Empirical Formula (Hill Notation): C₂₁H₃₆O₃
• CAS Number: 1098-45-9
• Molecular Weight: 336.51
• Beilstein: 2619975
• EC Number: 214-148-0
• MDL number: MFCD00003678
• UNSPSC Code: 12352202
• PubChem Substance ID: 24898959
• NACRES: NA.77

Properties

• Assay: ≥98.00% (TLC)
• Quality Level: 200
• form: powder
• solubility: chloroform: methanol (1:1): 19.60-20.40 mg/mL, clear, colorless
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@@]4(C)[C@@]3([H])CC[C@]4(O)[C@H](C)O)[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C21H36O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h13-18,22-24H,4-12H2,1-3H3/t13-,14+,15+,16+,17-,18-,19-,20-,21-/m0/s1
• InChI key: SCPADBBISMMJAW-UHHUKTEYSA-N

Description

General description

5β-Pregnane-3α,17α,20α-triol (pregnanetriol) is a urinary steroid metabolite of 17α-hydroxyprogesterone.

Biochem/physiol Actions

5β-Pregnane-3α,17α,20α-triol (pregnanetriol) plays a role in the synthesis of adrenal corticoids. Levels of pregnanetriol are elevated in the urine of 21-hydroxylase deficiency and congenital adrenal hyperplasia (CAH) patients.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves