K4639

Anti-Potassium Channel K_v1.7 antibody produced in rabbit

affinity isolated antibody, lyophilized powder

• Synonym(s): Anti-KCNA7, Anti-Voltage gated K⁺ channel KV1.7
• MDL number: MFCD09753859
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• should not react with: human
• technique(s): western blot: 1:200 using heart membranes
• UniProt accession no.: Q17ST2
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: mouse ... Kcna7(16495)

Description

Immunogen

peptideTTRKAQEIHGKAPG (C) corresponding to residues 2-15 of mouse Kv1.7.

Target description

K_v1.7 voltage-gated K⁺ channel is a member of the Shaker family of K⁺ channels that includes eight members (K_v1.1- K_v1.8). The biophysical and pharmacological properties of the K_v1.7 channel closely resemble that of the ultra-rapidly activating delayed rectifier (I_Kur) in cardiac tissue. This current plays a central role in cardiac atria repolarization that was largely believed to correspond to the activity of the K_v1.5 channel.

Physical form

Lyophilized powder from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.025% sodium azide.

Reconstitution

Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).

Safety Information

• Storage Class Code: 10 - Combustible liquids