B0560
(−)-Blebbistatin
≥98% (HPLC), solid, cell cycle inhibitor
Synonym(s):
1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2.3-b]-7-methylquinolin-4-one
About This Item
Recommended Products
product name
(−)-Blebbistatin, solid, synthetic
Quality Level
form
solid
solubility
DMSO: 5 mg/mL
chloroform: soluble(lit.)
ethyl acetate: soluble(lit.)
methanol: soluble(lit.)
methylene chloride: soluble(lit.)
storage temp.
−20°C
SMILES string
Cc1ccc2N=C3N(CC[C@@]3(O)C(=O)c2c1)c4ccccc4
InChI
1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m1/s1
InChI key
LZAXPYOBKSJSEX-GOSISDBHSA-N
General description
Application
Biochem/physiol Actions
Features and Benefits
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment
Certificates of Analysis (COA)
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n proliferating cells, the cell cycle consists of four phases. Gap 1 (G1) is the interval between mitosis and DNA replication that is characterized by cell growth. Replication of DNA occurs during the synthesis (S) phase, which is followed by a second gap phase (G2) during which growth and preparation for cell division occurs. Together, these three stages comprise the interphase phase of the cell cycle. Interphase is followed by the mitotic (M) phase.
Apoptosis, or programmed cell death (PCD), is a selective process for the removal of unnecessary, infected or transformed cells in various biological systems. As it plays a role in the homeostasis of multicellular organisms, apoptosis is tightly regulated through two principal pathways by a number of regulatory and effector molecules.
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