A9298

Methyl arachidonate

≥99% (GC)

• Synonym(s): Arachidonic acid methyl ester
• Empirical Formula (Hill Notation): C₂₁H₃₄O₂
• CAS Number: 2566-89-4
• Molecular Weight: 318.49
• Beilstein: 1714445
• MDL number: MFCD00016775
• UNSPSC Code: 12352211
• PubChem Substance ID: 24891434
• NACRES: NA.25

Properties

• biological source: Mortierella alpina
• Assay: ≥99% (GC)
• form: liquid
• functional group: ester
• lipid type: omega FAs
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC
• InChI: 1S/C21H34O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21(22)23-2/h7-8,10-11,13-14,16-17H,3-6,9,12,15,18-20H2,1-2H3/b8-7-,11-10-,14-13-,17-16-
• InChI key: OFIDNKMQBYGNIW-ZKWNWVNESA-N

Description

Application

• Lipid peroxidation products mediate the formation of 8-hydroxydeoxyguanosine in DNA.: This article explores the role of lipid peroxidation products, specifically those involving methyl arachidonate, in causing oxidative DNA damage, indicating the compound′s influence on cellular aging and disease processes (Park JW et al., 1992).

Biochem/physiol Actions

Unlike most unsaturated fatty acid methyl esters, methyl arachidonate is a potent activator of protein kinase C at 5–50 μM. At the low end of the effective concentration range, the effect is due to cyclooxygenase products, while lipoxygenase products mediate the effect at higher concentrations.

Packaging

Sealed ampule under vacuum.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves