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Key Documents

40231

Sigma-Aldrich

N,N-Dimethyldodecylamine N-oxide solution

BioUltra, ~0.1 M in H2O

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

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About This Item

Empirical Formula (Hill Notation):
C14H31NO
CAS Number:
Molecular Weight:
229.40
Beilstein:
1769927
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

product line

BioUltra

form

liquid

mol wt

229.40 g/mol

concentration

~0.1 M in H2O

technique(s)

PCR: suitable

impurities

insoluble matter, passes filter test
≤0.005% peroxides (as H2O2)

refractive index

n20/D 1.336

pH

7.0-9.0 (25 °C, 0.1 M in H2O)

density

0.996 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Al: ≤1 mg/kg
As: ≤0.1 mg/kg
Ba: ≤1 mg/kg
Bi: ≤1 mg/kg
Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Mo: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

λ

0.1 M in H2O

UV absorption

λ: 260 nm Amax: ≤0.07
λ: 280 nm Amax: ≤0.06

SMILES string

CCCCCCCCCCCC[N+](C)([O-])C

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

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Other Notes

Non-ionic detergent with wide application in biochemistry. Isolation and purification of gap junction channels; Completely solubilizes membrane-embedded phosphorhodopsin; Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into 2 subcomplexes.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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K A Stauffer et al.
The Journal of cell biology, 115(1), 141-150 (1991-10-01)
This paper reports methods we have developed to solubilize gap junction channels, or connexons, from isolated gap junctions and to purify them in milligram quantities. Two sources of material are used: rat liver gap junctions and gap junctions produced by
K R Dean et al.
European journal of biochemistry, 213(2), 881-890 (1993-04-15)
A protocol for the separation of phosphorhodopsin from phospho-opsin has been developed. The method takes advantage of the finding that, while 0.5% N,N-dimethyldodecylamine-N-oxide completely solubilises membrane-embedded phosphorhodopsin, at this concentration of detergent, phospho-opsin is only sparingly soluble. Phosphorhodopsin solubilised in
M Finel et al.
Biochemistry, 31(46), 11425-11434 (1992-11-24)
NADH:ubiquinone oxidoreductase (complex I) was purified from bovine heart mitochondria by solubilization with n-dodecyl beta-D-maltoside (lauryl maltoside), ammonium sulfate fractionation, and chromatography on Mono Q in the presence of the detergent. Its subunit composition was very similar to complex I
M Finel et al.
European journal of biochemistry, 226(1), 237-242 (1994-11-15)
Enzymically active subcomplexes were purified from bovine mitochondrial NADH:ubiquinone oxidoreductase (complex I) by sucrose-gradient centrifugation in the presence of detergents. These subcomplexes, named I lambda, IS, and I lambda S, catalyse ferricyanide and ubiquinone-1 (Q-1) reduction by NADH at similar
Eugenio Daviso et al.
Journal of the American Chemical Society, 133(42), 16754-16757 (2011-10-04)
Several techniques rely on electron-nuclear interactions to boost the polarization of nuclear spins in the solid phase. Averaging out of anisotropic interactions as a result of molecular tumbling strongly reduces the applicability of such hyperpolarization approaches in liquids. Here we

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