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525235

Sigma-Aldrich

Celpure® P65

meets USP/NF testing specifications

Synonym(s):

Diatomaceous earth, Diatomaceous silica, Kieselguhr

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About This Item

CAS Number:
61790-53-2
MDL number:
MFCD00132803
UNSPSC Code:
11101527
PubChem Substance ID:
329757849
NACRES:
NA.21

Agency

meets USP/NF testing specifications

form

solid

specific activity

≤1 EU/g (endotoxin)

composition

SiO2, 98%

parameter

0.065 (Permeability)

particle size

~0.20 mm

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Celpure® P65 (Diatomaceous earth, DE) is natural amorphous silica formed from the fossilized skeletons of diatoms. It is extracted, crushed, dried and calcined with or without flux material. DE is widely used as filler in construction materials, paints and as an anti-caking agent for agricultural chemicals. It has high water and oil absorption ability. The potential toxicity of different samples of DE has been assessed. DE is also employed as an adsorbent for column chromatography.

Application

For high-purity, high-throughput processes
Highly insoluble, inert material for use as a filtration aid.

Legal Information

Product of Imerys Filtration Minerals
Celpure is a registered trademark of Advanced Minerals Corporation

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The global variability of diatomaceous earth toxicity: a physicochemical and in vitro investigation.
Nattrass C, et al.
Journal of Occupational Medicine and Toxicology (London, England), 10(1), 25-25 (2015)
Manpreet Bariana et al.
International journal of pharmaceutics, 443(1-2), 230-241 (2013-01-05)
Diatomaceous earth (DE), or diatomite silica microparticles originated from fossilized diatoms are a potential substitute for its silica-based synthetic counterparts to address limitations in conventional drug delivery. This study presents the impact of engineered surface chemistry of DE microparticles on
James F Meadow et al.
Microbial ecology, 65(1), 171-179 (2012-08-29)
Geothermal influenced soils exert unique physical and chemical limitations on resident microbial communities but have received little attention in microbial ecology research. These environments offer a model system in which to investigate microbial community heterogeneity and a range of soil
Goran G Andrić et al.
Journal of economic entomology, 105(2), 670-678 (2012-05-23)
Insecticidal potential of natural zeolites and diatomaceous earths originating from Serbia against Sitophilus oryzae (L.) and Tribolium castaneum (Herbst) was evaluated. Two natural zeolite formulations (NZ and NZ Modified) were applied to wheat at rates of 0.50, 0.75, and 1.0
Trevor A Lambkin et al.
Journal of economic entomology, 105(3), 979-987 (2012-07-21)
Spinosad, diatomaceous earth, and cyfluthrin were assessed on two broiler farms at Gleneagle and Gatton in southeastern Queensland, Australia in 2004-2005 and 2007-2009, respectively to determine their effectiveness in controlling lesser mealworm, Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae). Insecticide treatments were
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