T1820002

Trapidil impurity A

European Pharmacopoeia (EP) Reference Standard

• Synonym(s): 7-Hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidine, 5-Methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-ol, 6-Methyl-4-hydroxy-1,3,3a,7-tetraazaindene, 7-Hydroxy-5-methyl-1,3,4-triazaindolizine, NSC 32071, NSC 511493
• Empirical Formula (Hill Notation): C₆H₆N₄O
• CAS Number: 2503-56-2
• Molecular Weight: 150.14
• MDL number: MFCD00005555
• UNSPSC Code: 41116107
• PubChem Substance ID: 329826689
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: trapidil
• manufacturer/tradename: EDQM
• mp: 280-283 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cc1cc(O)n2ncnc2n1
• InChI: 1S/C6H6N4O/c1-4-2-5(11)10-6(9-4)7-3-8-10/h2-3,11H,1H3
• InChI key: ZUIVNYGZFPOXFW-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Reactant for the synthesis of:

• Ruthenium(II)-Hmtpo complexes
• Dihydroorotate dehydrogenase inhibitors with antimalarial activity

Reactant for the Vilsmeier reaction of conjugated carbocycles and heterocycles

Investigations of the pharmacological activity caused by binding to HIV TAR RNA

Additive to study the space charge layer in silver bromide microcrystals

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable