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Q0501

Sigma-Aldrich

Quin 2 potassium salt hydrate

≥95% purity, powder

Synonym(s):

2-([2-Bis(carboxymethyl)amino-5-methylphenoxy]methyl)-6-methoxy-8-bis(carboxymethyl)aminoquinoline

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About This Item

Empirical Formula (Hill Notation):
C26H27N3O10 · H2O
CAS Number:
Molecular Weight:
559.52
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Quin 2 potassium salt hydrate, ≥95%

Quality Level

Assay

≥95%

form

powder

solubility

1 M NaOH: 50 mg/mL, clear, yellow-green

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

O.[K].COc1cc(N(CC(O)=O)CC(O)=O)c2nc(COc3ccc(C)cc3N(CC(O)=O)CC(O)=O)ccc2c1

InChI

1S/C26H27N3O10.K.H2O.H/c1-15-3-6-21(19(7-15)28(10-22(30)31)11-23(32)33)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37;;;/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37);;1H2;

InChI key

UQTLVSNRWZMUEK-UHFFFAOYSA-N

Application

Calcium-specific chelator and indicator. Upon binding calcium there is a shift in the UV spectrum and an enhancement of fluorescence.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R Y Tsien et al.
The Journal of cell biology, 94(2), 325-334 (1982-08-01)
A new, fluorescent, highly selective Ca2+ indicator , "quin2", has been trapped inside intact mouse and pig lymphocytes, to measure and manipulate cytoplasmic free Ca2+ concentrations, [Ca2+]i. Quin2 is a tetracarboxylic acid which binds Ca2+ with 1:1 stoichiometry and an

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