P8721
Penicillin G potassium salt
Synonym(s):
Benzylpenicillin potassium salt
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About This Item
Empirical Formula (Hill Notation):
C16H17KN2O4S
CAS Number:
Molecular Weight:
372.48
Beilstein:
3832841
EC Number:
MDL number:
UNSPSC Code:
51283405
eCl@ss:
34010400
PubChem Substance ID:
NACRES:
NA.21
Recommended Products
form
crystalline powder
Quality Level
potency
1440-1680 units per mg
antibiotic activity spectrum
Gram-positive bacteria
application(s)
pharmaceutical (small molecule)
Mode of action
cell wall synthesis | interferes
SMILES string
[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
InChI
1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
InChI key
IYNDLOXRXUOGIU-LQDWTQKMSA-M
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General description
Chemical structure: ß-lactam
Application
Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Biochem/physiol Actions
Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.
Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.
Packaging
10mu,25mu,100mu
Caution
Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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