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O8001

Sigma-Aldrich

Octyl β-D-glucopyranoside

≥98% (GC)

Synonym(s):

n-Octyl glucoside, OGP

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About This Item

Empirical Formula (Hill Notation):
C14H28O6
CAS Number:
Molecular Weight:
292.37
Beilstein:
84118
EC Number:
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.21

description

non-ionic

Quality Level

Assay

≥98% (GC)

form

powder

mol wt

micellar avg mol wt 25,000

aggregation number

84

CMC

20-25 mM (20-25°C)

transition temp

cloud point >100 °C

storage temp.

−20°C

SMILES string

CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1

InChI key

HEGSGKPQLMEBJL-RKQHYHRCSA-N

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Application

Octyl β --D-glucopyranoside has been used:
  • In varying concentrations to wash Sepharose beads to study the interaction of Albumin-shFcRn in the presence of Octyl β-D-glucopyranoside
  • As a lysis and solubilization solution for bacterial lipoprotein preparation
  • To solubilize the recombinant 47 kDa antigen from E. coli cell
  • As a component of lysis buffer for determination of protein content by BCA assay
  • In deglycolysation process
  • As a component of lysis buffer to prepare mitochondrial extracts
Non-ionic, dialyzable detergent for the solubilization and isolation of membrane proteins. Has been shown to increase the resolution of proteins in 2D gels.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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IL-10 Prevents apoptosis of brain endothelium during bacteremia.
Londo?o D, et al.
Journal of Immunology, 1100060-1100060 (2011)
Genetic and physicochemical characterization of the recombinant DNA-derived 47-kilodalton surface immunogen of Treponema pallidum subsp. pallidum.
Chamberlain N R, et al.
Infection and Immunity, 56(1), 71-78 (1988)
Insulin and AMPK regulate fatty acid translocase/CD36 plasma membrane recruitment in cardiomyocytes via RabGAP AS160 and Rab8a Rab GTPase.
Journal of Lipid Research, jlr-M023424 (2012)
The major histocompatibility complex?related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan.
The Journal of Experimental Medicine, 197(3), 315-322 (2003)
Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo.
Samovski D, et al.
The Journal of Biological Chemistry, 285(10), 6879-6890 (2010)

Protocols

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