UFC710008
Centricon® Plus Centrifugal Filter
MWCO 100 kDa, sample volume 15-70 mL, regenerated cellulose membrane
Synonym(s):
Centrifuge concentrator
About This Item
Recommended Products
material
polypropylene cap
polypropylene cup (for concentrate/retentate)
polypropylene cup (for filtrate collection)
polypropylene cup (for sample filter)
regenerated cellulose membrane
Quality Level
sterility
non-sterile
product line
Amicon®
feature
holdup volume 75 μL
manufacturer/tradename
Amicon® Ultra
Centricon®
parameter
15-70 mL sample volume
technique(s)
protein extraction: suitable
protein purification: suitable
L
121 mm
diam.
6 cm
filtration area
19 cm2
pore size
100 kDa MWCO
application(s)
sample preparation
shipped in
ambient
General description
The Centricon Plus-70 centrifugal filter is a disposable, single-use device designed for the processing of aqueous biological solutions in volumes ranging from 15 to 70 mL.
Application
Features and Benefits
- compatiblewith swinging-bucket centrifuges only
- can concentrate most 70 mL solutionsdown to 350 µL in 15-40 minutes
Physical form
Other Notes
Legal Information
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Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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Articles
Large-volume centrifugal filter devices are a convenient alternative to stirred cell ultrafiltration devices for purifying proteins from large volumes of solution.
This page discusses the principles and benefits of using ultrafiltration membranes in protein sample preparation. Possible applications include solvent exchange, protein sample concentration, or sample purification.
Protocols
Monoclonal antibodies (MAb) continue to gain importance as therapeutic and diagnostic agents for many cancers. The process of screening hybridoma libraries for candidate MAbs typically requires several days to complete and can be labor-intensive when evaluating multiple MAbs in parallel. Ultrafiltration-based MAb purification, on the other hand, is easier, faster (2–3 hours versus 2 days), and yields higher recoveries.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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