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Key Documents

16-272

Sigma-Aldrich

Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate

clone 4G12, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

4G12, monoclonal

species reactivity (predicted by homology)

all

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable

shipped in

wet ice

target post-translational modification

acetylation (Lys)

Specificity

Recognizes acetyl lysine-containing proteins including histones.

Immunogen

A mixture of chemically acetylated antigens. Clone 4G12.

Application

Detect acetyl Lysine with Anti-acetyl Lysine Antibody, clone 4G12, agarose conjugate (Mouse Monoclonal Antibody), that has been shown to work in IP.
Research Category
Signaling

Epigenetics & Nuclear Function
Research Sub Category
General Post-translation Modification

Histones

Features and Benefits

Format: Gel Immobilized

Quality

Routinely evaluated by immunoprecipitating

Target description

varies depending upon the protein being detected

Storage and Stability

1 year at 4°C from date of shipment. DO NOT FREEZE.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N Munshi et al.
Molecular cell, 2(4), 457-467 (1998-11-11)
The transcriptional coactivators CBP and P/CAF are required for activation of transcription from the IFN beta enhanceosome. We show that CBP and P/CAF acetylate HMG I(Y), the essential architectural component required for enhanceosome assembly, at distinct lysine residues, causing distinct
Acetylation of general transcription factors by histone acetyltransferases.
Imhof, A, et al.
Current Biology, 7, 689-692 (1997)

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