14-444-M
PKC θ Protein, active, 10 µg
Active, recombinant full-length human PKC theta with a C-terminal 6His-tag. For use in Kinase Assays.
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41
biological source
human
Quality Level
recombinant
expressed in Sf21 cells
mol wt
Mw 83 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
NCBI accession no.
UniProt accession no.
Gene Information
human ... PRKCQ(5588)
General description
Product Source: expressed in Sf21 cells
Recombinant full-length human PKC theta with a C-terminal 6His-tag
PKC Lipid activator (Catalog # 20-133) is required for use.
PKC Lipid activator (Catalog # 20-133) is required for use.
Biochem/physiol Actions
Protein Target: PKCθ
Target Sub-Family: AGC
Quality
routinely evaluated by phosphorylation of Histone H1 substrate in vitro
Physical form
immobilized nickel affinity chromatography
Storage and Stability
6 months at -70 °C
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Sens. 1
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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G Baier et al.
The Journal of biological chemistry, 268(7), 4997-5004 (1993-03-05)
Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types and, to date, the cloning of seven mammalian PKC genes encoding eight distinct isoforms has
B Bauer et al.
The Journal of biological chemistry, 276(34), 31627-31634 (2001-06-19)
Protein kinase C theta (PKC theta) is known to induce NF-kappa B, an essential transcriptional element in T cell receptor/CD28-mediated interleukin-2 production but also T cell survival. Here we provide evidence that PKC theta is physically and functionally coupled to
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