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780200P

Avanti

16:0 PE MCC

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)

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About This Item

Empirical Formula (Hill Notation):
C49H86N2O11PNa
CAS Number:
Molecular Weight:
933.18
UNSPSC Code:
12352211
NACRES:
NA.25

Pricing and availability is not currently available.

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (780200P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 780200P

shipped in

dry ice

storage temp.

−20°C

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This Item
780200C780201P780201C
manufacturer/tradename

Avanti Research - A Croda Brand 780200P

manufacturer/tradename

Avanti Research - A Croda Brand 780200C

manufacturer/tradename

Avanti Research - A Croda Brand 780201P

manufacturer/tradename

Avanti Research - A Croda Brand 780201C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

packaging

pkg of 1 × 25 mg (780200P-25mg)

packaging

pkg of 1 × 2.5 mL (780200C-25mg)

packaging

pkg of 1 × 100 mg (780201P-100mg), pkg of 1 × 25 mg (780201P-25mg)

packaging

pkg of 1 × 2.5 mL (780201C-25mg)

form

powder

form

liquid

form

powder

form

liquid

General description

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (16:0 PE MCC) is a lipid consisting of phosphoethanolamine linked to two palmitic acid through its phosphate group and to a maleimide group by its amino group. It is a maleimide-functionalized lipid.[1]

Application

16:0 PE MCC (1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide]) may been used in functionalized liposome preparation for drug delivery.[2] It may also be used in liposome preparation for testing drug delivery functionality[1] and as a component in microbubble dispersions.[3]

Biochem/physiol Actions

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide](DPPE-MCC) via the maleimide group enables covalent attachment in functionalized liposomes and is useful in peptide transport studies.[2]

Packaging

5 mL Amber Glass Screw Cap Vial (780200P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


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    Astrid Hilde Myrset et al.
    Ultrasound in medicine & biology, 37(1), 136-150 (2010-12-15)
    Targeted ultrasound (US) contrast agents represent, because of their size (1 to 5 μm), a unique class of diagnostic imaging agents enabling true vascular imaging of conditions like inflammation and tumor angiogenesis. The objective of this study was to develop
    K Gradauer et al.
    Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
    The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
    K Gradauer et al.
    Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
    An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to

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