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I3875

Sigma-Aldrich

Indoxyl sulfate potassium salt

Synonym(s):

Potassium 3-indoxyl sulfate, Urinary indican

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About This Item

Linear Formula:
C8H6NO4SK
CAS Number:
2642-37-7
Molecular Weight:
251.30
Beilstein:
3921324
EC Number:
220-145-5
MDL number:
MFCD00037931
UNSPSC Code:
12352100
PubChem Substance ID:
57654302
NACRES:
NA.22

mp

165 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

[K+].[O-]S(=O)(=O)Oc1c[nH]c2ccccc12

InChI

1S/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1

InChI key

MDAWATNFDJIBBD-UHFFFAOYSA-M

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General description

Indoxyl sulfate potassium salt is derived from indoxyl sulfate by replacing the hydrogen ion with a potassium cation. Potassium indoxyl sulfate is used as a reagent for the detection and determination of hydrogen peroxide.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Bummei Sato et al.
The American journal of cardiology, 111(5), 712-716 (2012-12-12)
The prognosis of patients with diastolic heart failure (HF) is as poor as that of patients with systolic HF. Greater chronic kidney disease-associated mortality occurs in patients with left ventricular (LV) diastolic HF than in those with systolic HF. Indoxyl
Tetsuhiro Tanaka et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(10), 4059-4075 (2013-06-25)
Chronic hypoxia in the tubulointerstitium serves as a final common pathway in progressive renal disease. Circumstantial evidence suggests that hypoxia-inducible factor (HIF)-1 in the ischemic tubules may be functionally inhibited in a chronic kidney disease (CKD) milieu. In this study
Carel J Pretorius et al.
Clinica chimica acta; international journal of clinical chemistry, 419, 122-126 (2013-02-23)
The uremic toxins indoxyl sulphate (IS) and p-cresyl sulphate (pCS) are absorbed bacterial metabolites of tryptophan and tyrosine respectively and may be predictive of clinical outcome. Long chromatography times, incomplete data on the reference ranges of the free and total
Liesbeth Viaene et al.
American journal of nephrology, 36(6), 497-508 (2012-11-23)
Local production of 1,25-dihydroxyvitamin D (1,25(OH)(2)D) regulated by the CYP27B1 enzyme in monocytes contributes to the immunomodulatory effects of vitamin D. Uremia suppresses renal CYP27B1, but its impact on monocytic CYP27B1 is incompletely understood. The present study aimed to elucidate
Maimaiti Yisireyili et al.
Life sciences, 92(24-26), 1180-1185 (2013-05-25)
Cardiovascular disease (CVD) is common in chronic kidney disease (CKD) patients. Indoxyl sulfate (IS) is a nephrovascular uremic toxin that induces oxidative stress in kidney and vascular system. The present study aimed to examine the effect of IS on fibrosis
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