B2761

5-Bromoindole-2-carboxylic acid

98%

• Synonym(s): NSC 73384
• Linear Formula: C₉H₆NO₂Br
• CAS Number: 7254-19-5
• Molecular Weight: 240.05
• MDL number: MFCD00022705
• UNSPSC Code: 12352100
• PubChem Substance ID: 57653927
• NACRES: NA.22

Properties

• Assay: 98%
• form: powder
• storage temp.: −20°C
• SMILES string: OC(=O)c1cc2cc(Br)ccc2[nH]1
• InChI: 1S/C9H6BrNO2/c10-6-1-2-7-5(3-6)4-8(11-7)9(12)13/h1-4,11H,(H,12,13)
• InChI key: YAULOOYNCJDPPU-UHFFFAOYSA-N

Description

Application

Reactant involved in studies of biologically active molecules including:

• Discovery of indole inhibitors of MMP-13 for treatment of arthritic diseases
• Synthesis of indolyl ethanones as indoleamine 2,3-dioxygenase inhibitors
• cis-Diaminocyclohexane derivatives prepared for use as factor Xa inhibitors
• Synthesis of tubulin polymerization inhibitors and cancer cell growth inhibitors
• Preparation of dual PPARγ/δ agonists
• Synthesis of chemical probes to examine the role of hFPRL1 receptor in inflammation

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves