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Sigma-Aldrich

1-Methyl-2-azaadamantane-N-oxyl

greener alternative

97%

Synonym(s):

1-Me-AZADO

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About This Item

Empirical Formula (Hill Notation):
C10H16NO
CAS Number:
Molecular Weight:
166.24
UNSPSC Code:
12352000
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

solid

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

87-93 °C

greener alternative category

storage temp.

2-8°C

SMILES string

CC12CC3CC(CC(C3)N1[O])C2

InChI

1S/C10H16NO/c1-10-5-7-2-8(6-10)4-9(3-7)11(10)12/h7-9H,2-6H2,1H3

InChI key

IBNXYCCLPCGKDM-UHFFFAOYSA-N

General description

1-Methyl-2-azaadamantane-N-oxyl (1-Me-AZADO), a sterically less hindered nitroxyl radical, is widely used as catalyst. It is chemically stable and exhibits superior catalytic performance.
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Application

1-Methyl-2-azaadamantane-N-oxyl (1-Me-AZADO) may be employed as catalyst for the aerobic oxidation of alcohols and sterically hindered alcohols.
Catalytic oxidant for greener oxidation of alcohols under aerobic, solvent-free conditions. Recoverable and recyclable.

Solvent free aerobic oxidation of alcohols with 1-methyl-2-azaadamantane N-oxyl as a recyclable catalyst through phase separation

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Solvent free aerobic oxidation of alcohols with 1-methyl-2-azaadamantane N-oxyl as a recyclable catalyst through phase separation.
Kuang Y, et al.
Green Chemistry, 13(7), 1659-1663 (2011)
Efficient oxidation of alcohols electrochemically mediated by azabicyclo-N-oxyls.
Demizu Y, et al.
Tetrahedron Letters, 49(1), 48-52 (2008)

Articles

TEMPO (2,2,6,6-Tetramethylpiperidinyloxy or 2,2,6,6-Tetramethylpiperidine 1-oxyl) and its derivatives are stable nitroxy radicals used as catalysts in organic oxidation reactions. TEMPO was discovered by Lebedev and Kazarnovskii in 1960. The stable free radical nature of TEMPO is due to the presence of bulky substituent groups, which hinder the reaction of the free radical with other molecules.

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