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687537

Sigma-Aldrich

Poly(ethylene glycol) dimethacrylate

average MN 6,000, cross-linking reagent polymerization reactions, methacrylate, 1000 ppm 4-methoxyphenol as inhibitor

Synonym(s):

Polyethylene glycol, PEG dimethacrylate

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About This Item

Linear Formula:
C3H5C(O)(OCH2CH2)nOC(O)C3H5
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) dimethacrylate, average Mn 6,000, contains 1000 ppm 4-methoxyphenol as inhibitor

form

powder

Quality Level

mol wt

average Mn 6,000

contains

1000 ppm 4-methoxyphenol as inhibitor

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

bp

>200 °C/2 mmHg (lit.)

transition temp

Tm 50.2-53.7 °C

Mw/Mn

<1.2

Ω-end

methacrylate

α-end

methacrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

SMILES string

OCCO.CC(=C)C(O)=O

InChI

1S/C10H14O4/c1-7(2)9(11)13-5-6-14-10(12)8(3)4/h1,3,5-6H2,2,4H3

InChI key

STVZJERGLQHEKB-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1


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Articles

In this article, we will discuss the benefits and limitations of several 2D and 3D scaffold patterning techniques that can be applied in the presence of cells. Although these methods will be discussed in the context of poly(ethylene glycol) (PEG)-based hydrogels, they can technically be applied to any optically transparent, photoactive substrate.

Highlighting new synthetic modifications of PEG to improve the mechanical properties and degradation of resulting hydrogels in tissue engineering applications.

The use of hydrogel-based biomaterials for the delivery and recruitment of cells to promote tissue regeneration in the body is of growing interest. This article discussed the application of hydrogels in cell delivery and tissue regeneration.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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