634786

(S)-(+)-N-Boc-3-pyrrolidinol

97%

• Synonym(s): (S)-N-(tert-Butoxycarbonyl)-(+)-3-pyrrolidinol
• Empirical Formula (Hill Notation): C₉H₁₇NO₃
• CAS Number: 101469-92-5
• Molecular Weight: 187.24
• MDL number: MFCD01317839
• UNSPSC Code: 12352005
• PubChem Substance ID: 24882649
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• optical activity: [α]20/D +26°, c = 1% in methanol
• mp: 60-64 °C (lit.)
• SMILES string: CC(C)(C)OC(=O)N1CC[C@H](O)C1
• InChI: 1S/C9H17NO3/c1-9(2,3)13-8(12)10-5-4-7(11)6-10/h7,11H,4-6H2,1-3H3/t7-/m0/s1
• InChI key: APCBTRDHCDOPNY-ZETCQYMHSA-N

Description

Application

(S)-(+)-N-Boc-3-pyrrolidinol can be used as a reactant to synthesize:

• tert-Butyl 3-(2-bromophenoxy)pyrrolidine-1-carboxylate, which is employed as a key intermediate in the preparation of IkB-kinase IKK2 inhibitor.
• Dimethoxy-pyrrolidylquinazoline , and peptidomimetic quinoline derivatives.

Safety Information

• Pictograms: GHS06,GHS05
• Signal Word: Danger
• Hazard Statements: H301,H315,H318,H335
• Precautionary Statements: P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 3 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves