534579

(R)-(−)-2-Amino-1-pentanol

97%

• Synonym(s): D-Norvalinol
• Linear Formula: CH₃(CH₂)₂CH(NH₂)CH₂OH
• CAS Number: 80696-30-6
• Molecular Weight: 103.16
• MDL number: MFCD02683228
• UNSPSC Code: 12352116
• PubChem Substance ID: 24878046
• NACRES: NA.22

Properties

• Assay: 97%
• optical activity: [α]20/D −17°, c = 1 in chloroform
• mp: 44-48 °C (lit.)
• SMILES string: CCC[C@@H](N)CO
• InChI: 1S/C5H13NO/c1-2-3-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m1/s1
• InChI key: ULAXUFGARZZKTK-RXMQYKEDSA-N

Description

Application

(R)-(-)-2-Amino-1-pentanol can be used as a chiral building block to prepare:

• A key intermediate, (R)-N-(p-toluenesulfonyl)-2-propylaziridine, which is utilized in the total synthesis of (R)-1-(benzofuran-2-yl)-2-propylaminopentane.
• (R)-N-benzyloxycarbonyl-aminoaldehydes as potential substrates for dihydroxyacetone phosphate (DHAP)-dependent aldolases.
• (R)-2-((2-Aminoquinazolin-4-yl)amino)pentan-1-ol as a potent dual toll-like receptor and modulator.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): 204.8 °F - closed cup
• Flash Point(C): 96 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves