Skip to Content
Merck
All Photos(4)

Key Documents

WH0158158M1

Sigma-Aldrich

Monoclonal Anti-RASEF antibody produced in mouse

clone 2D5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-FLJ31614, Anti-RAB45, Anti-RAS and EF-hand domain containing

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2D5, monoclonal

form

buffered aqueous solution

species reactivity

human, rat, mouse

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG2bκ

GenBank accession no.

BC023566

UniProt accession no.

Q8IZ41

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RASEF(158158)

General description

The gene encoding RAS and EF-hand domain containing protein (RASEF) is located on human chromosome 9q21 and is a tumor suppressor gene.

Immunogen

RASEF (AAH23566, 631 a.a. ~ 740 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
NIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSITNLTGTNSKKSPQMKNCCNG

Biochem/physiol Actions

RAS and EF-hand domain containing protein (RASEF) maybe involved in the Ras pathway. It associates with guanine nucleotide tri- and di-phosphates.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
11200-2D5
07124-2D5

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.
Shintani M
Biochemical and Biophysical Research Communications, 357(3), 661-667 (2007)
Willem Maat et al.
Investigative ophthalmology & visual science, 49(4), 1291-1298 (2008-04-04)
Recently, a segregation study in families with uveal and cutaneous melanoma identified 9q21 as a potential locus harboring a tumor-suppressor gene (TSG). One of the genes in this area, RASEF, was then analyzed as a candidate TSG, but lack of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service